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Pharmacovigilance Operations Manager

May 29, 2026

Position Summary: We are seeking a collaborative, proactive, and detail-oriented Manager, Pharmacovigilance Operations to lead patient safety operations across a diverse product portfolio. This role serves as a key contributor within the Patient Safety organization and is responsible for leading day-to-day pharmacovigilance operations, supporting safety surveillance activities, ensuring compliance with global regulations, and maintaining inspection-ready processes and systems. The individual will partner closely with Clinical Development, Regulatory Affairs, Medical Information, Quality, Medical Affairs, Customer Support, external vendors, and global stakeholders to support compliant and efficient safety operations. The ideal candidate brings deep pharmacovigilance operations expertise, strong project leadership capabilities, and a passion for process excellence within a fast-paced and evolving environment. Key Responsibilities: <ul> <li>Leads global Patient Safety Operations and effectively manages select safety surveillance projects for multiple product categories, including prescription drugs, class I, II, and III medical devices, OTC drugs, and cosmetics.</li> </ul> Safety Operations <ul> <li>Manages communications with vendors, CROs, QPPVs, and partners regarding the evaluation, processing, and reconciliation of case reports (ICSRs, MDRs, cosmetic AE reports).</li> <li>Manages communications with the clinical development team regarding safety data exchange and reconciliation between clinical and safety databases for clinical studies.</li> <li>Ensures that all safety reports received by the Patient Safety group from any source are processed and reported according to ICH-GCP guidelines, regulatory requirements and company SOPs and procedures.</li> <li>Reviews all cases to ensure the accuracy, integrity and completeness of information entered in the safety database.</li> <li>Ensures that expedited and non-expedited safety reports are submitted to regulatory authorities and partner companies as required and on time.</li> <li>Maintains the company electronic safety reporting portal, collates suggested inputs from cross-functional groups, and communicates with IT to ensure appropriate implementation.</li> <li>Leads PV compliance monitoring.</li> <li>Maintains the company core Pharmacovigilance System Master File (PSMF). Collates inputs from relevant cross-functional partners and updates the PSMF quarterly. Coordinates regional PSMF updates with QPPVs.</li> <li>Maintains and updates PV SOPs, vendor Joint Operating Guidelines (JOGs) and relevant departmental policies.</li> <li>Ensures continuous inspection and audit readiness of the Revance pharmacovigilance system by maintaining compliant processes, complete and inspection-ready documentation, effective vendor oversight, and measurable quality and compliance metrics.</li> </ul> Safety Surveillance <ul> <li>Monitors and identifies possible trends and concerns related to the use of Revance products, and key competitor products, including the identification and evaluation of safety signals through the assessment of single case reports, aggregate safety reports and review of relevant literature for safety information pertinent to product safety.</li> <li>Leads signal detection and analysis, as well as preparation and submission of signal reports.</li> </ul> Required Qualifications <ul> <li>Master's degree in Life Sciences, Pharmacology, Public Health, Nursing, or a related scientific field with 6–8+ years of pharmacovigilance experience, OR Bachelor's degree with 8+ years of relevant experience</li> <li>Progressive experience within pharmaceutical, biotechnology, or medical device environments</li> <li>Direct experience with:</li> <ul> <li>End-to-end case processing and ICSR/MDR lifecycle management</li> <li>Safety databases (Argus preferred)</li> <li>Signal detection and safety surveillance activities</li> </ul> <li>Strong understanding of:</li> <ul> <li>Global GVP regulations and ICH guidelines</li> <li>Pharmacovigilance compliance requirements</li> <li>Regulated processes and clinical trial lifecycle</li> </ul> <li>Experience analyzing and interpreting safety data and assessing clinical relevance</li> <li>Demonstrated ability to manage multiple priorities and lead projects independently</li> <li>Strong cross-functional collaboration and relationship management skills</li> <li>Excellent written and verbal communication skills</li> <li>High attention to detail and strong organizational skills</li> </ul> Preferred: <ul> <li>Completed MD, PhD, or PharmD degree with 2 or more years of clinical or academic experience and 3 or more years of patient safety experience in a pharmaceutical or medical device company</li> <li>Strong understanding of: <ul> <li>Audit and inspection management</li> <li>Risk management plans (RMPs)</li> <li>Company Core Data Sheet (CCDS) development</li> </ul> </li> <li>Hands-on experience with regulatory inspections, internal and external audits</li> <li>Exposure to global PV systems and multi-region compliance</li> <li>Experience with new market entries</li> <li>Experience developing aggregate reports (PSUR/PBRER, DSUR)</li> </ul> Company Summary: Revance is a global company developing, producing, and distributing industry-leading, differentiated products across aesthetics, skincare, and therapeutics. Revance drives innovation beyond convention to offer treatment options for individuals across generations. The Company’s vision is to redefine excellence in aesthetics, skincare, and therapeutics through science-powered innovation, with an unwavering commitment to its providers, patients, and consumers. Revance’s award-winning products are the result of robust research and development, a cornerstone for the Company, driven by renowned scientists. For more information about Revance, please visit us at www.revance.com. What Revance invests in you: <ul> <li>Competitive Compensation including base salary and annual performance bonus.</li> <li>Flexible PTO (12 days' PTO), holidays, and parental leave.</li> <li>Generous healthcare benefits, HSA match, 401k match, employer paid life and disability insurance, pet insurance, wellness discounts and much more!</li> </ul> This section of the job description is required by the American with Disability Act (ADA). The ADA requires that job descriptions reflect the physical and mental demands required to effectively perform the essential duties of the job. The ADA prohibits employers from discriminating against a “qualified individual with a disability” in all aspects of the employment relationship. A “qualified individual with a disability” is “an individual who meets the education, experience, skill, and other job-related requirements of a position held or desired, and who, with reasonable accommodation, can perform the essential functions of a specified job.” Revance is an Equal Opportunity employer. All qualified applicants will receive consideration for employment based on merit, without regard to race, color, religion, sex, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.

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Common Interview Questions And Answers

1. HOW DO YOU PLAN YOUR DAY?

This is what this question poses: When do you focus and start working seriously? What are the hours you work optimally? Are you a night owl? A morning bird? Remote teams can be made up of people working on different shifts and around the world, so you won't necessarily be stuck in the 9-5 schedule if it's not for you...

2. HOW DO YOU USE THE DIFFERENT COMMUNICATION TOOLS IN DIFFERENT SITUATIONS?

When you're working on a remote team, there's no way to chat in the hallway between meetings or catch up on the latest project during an office carpool. Therefore, virtual communication will be absolutely essential to get your work done...

3. WHAT IS "WORKING REMOTE" REALLY FOR YOU?

Many people want to work remotely because of the flexibility it allows. You can work anywhere and at any time of the day...

4. WHAT DO YOU NEED IN YOUR PHYSICAL WORKSPACE TO SUCCEED IN YOUR WORK?

With this question, companies are looking to see what equipment they may need to provide you with and to verify how aware you are of what remote working could mean for you physically and logistically...

5. HOW DO YOU PROCESS INFORMATION?

Several years ago, I was working in a team to plan a big event. My supervisor made us all work as a team before the big day. One of our activities has been to find out how each of us processes information...

6. HOW DO YOU MANAGE THE CALENDAR AND THE PROGRAM? WHICH APPLICATIONS / SYSTEM DO YOU USE?

Or you may receive even more specific questions, such as: What's on your calendar? Do you plan blocks of time to do certain types of work? Do you have an open calendar that everyone can see?...

7. HOW DO YOU ORGANIZE FILES, LINKS, AND TABS ON YOUR COMPUTER?

Just like your schedule, how you track files and other information is very important. After all, everything is digital!...

8. HOW TO PRIORITIZE WORK?

The day I watched Marie Forleo's film separating the important from the urgent, my life changed. Not all remote jobs start fast, but most of them are...

9. HOW DO YOU PREPARE FOR A MEETING AND PREPARE A MEETING? WHAT DO YOU SEE HAPPENING DURING THE MEETING?

Just as communication is essential when working remotely, so is organization. Because you won't have those opportunities in the elevator or a casual conversation in the lunchroom, you should take advantage of the little time you have in a video or phone conference...

10. HOW DO YOU USE TECHNOLOGY ON A DAILY BASIS, IN YOUR WORK AND FOR YOUR PLEASURE?

This is a great question because it shows your comfort level with technology, which is very important for a remote worker because you will be working with technology over time...